期刊简介
本刊是由广西医科大学主办的国内外公开发行的医学学术期刊。内容丰富，形式多样，科学性强，有实用性。主要设有论著、经验交流、调查研究、技术与方法、护理园地、病例报告等栏目。
往期目录
-
1999
-
2000
-
2001
-
2002
-
2003
-
2004
-
2005
-
2006
-
2007
-
2008
-
2009
-
2010
-
2011
-
2012
-
2013
-
2014
-
2015
-
2016
-
2017
-
2018
-
2019
首页>广西医科大学学报杂志
- 杂志名称：广西医科大学学报杂志
- 主管单位：广西医科大学
- 主办单位：广西医科大学
- 国际刊号：1005-930X
- 国内刊号：45-1211/R
- 出版周期：双月刊
期刊荣誉：全国高校自然科学优秀学报期刊收录：知网收录(中), 上海图书馆馆藏, 国家图书馆馆藏, 维普收录(中), 统计源核心期刊(中国科技论文核心期刊), 万方收录(中)
The expression and clinical significance of long non-coding RNA LOC728040in hepatocellular carcinoma
Xiaoyun Yang；Qian Liao；Xiaoqiang Qiu
关键词：Long non-coding RNA, LOC728040, qPCR, hepatocellular carcinoma
摘要：Objective:This study aimed to investigate the expression of long non-coding RNA LOC728040 in hepatocellular carcinoma (HCC) tissues and normal tissues.Methods:Quantitative reverse-transcription PCR (qPCR) was performed to detect the expression of LOC728040 in HCC tissues and paracancer tissues to explore the differences of the clinical indicators of HCC between two groups of low and high expression.And the target genes prediction of LOC728040 as a supplement.Results:The lower expression of LOC728040 was found in HCC tissues compared with the paracancer tissues (P ＜0.05).According to the expression,Patients were divided into two groups,and their occupation,tumor capsular and serum alkaline phosphatase(ALP) were significantly different (P ＜ 0.05).We found LOC728040 upstream existed an alpha albumin gene(AFM) through the Cis analysis by Blast software.Conclusion:Long non-coding RNA LOC728040 was markedly downregulated in HCC tissues and was correlated with occupation tumor capsular and serum ALP.The LOC728040 might be a biomarker for detection of HCC or other cancers,but its underlying mecha nisms still need further study.
友情链接