期刊简介
本刊是由广西医科大学主办的国内外公开发行的医学学术期刊。内容丰富，形式多样，科学性强，有实用性。主要设有论著、经验交流、调查研究、技术与方法、护理园地、病例报告等栏目。
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首页>广西医科大学学报杂志
- 杂志名称：广西医科大学学报杂志
- 主管单位：广西医科大学
- 主办单位：广西医科大学
- 国际刊号：1005-930X
- 国内刊号：45-1211/R
- 出版周期：双月刊
期刊荣誉：全国高校自然科学优秀学报期刊收录：知网收录(中), 上海图书馆馆藏, 国家图书馆馆藏, 维普收录(中), 统计源核心期刊(中国科技论文核心期刊), 万方收录(中)
Effects of resistant exercise on regulating the gutmicrobiota related to glucose control in mice with type 2 diabetes
Zhai Lu；Wei Wei；Liu Yuhua；Zhao Wenpiao；Huang Yanfeng；Ma Cui；Dai Xia
关键词：type 2 diabetes, gut microbiota, resistant exercise
摘要：Objective:To explore the effect of resistant exercise on improvement of gut microbiota regulating glucose control in mice with type 2 diabetes.Methods:Male mice with type 2 diabetes aged 8 weeks were randomly assigned to control group,aerobic training (AT)group and resistant training (RT) group.One month after the intervention,the blood glucose was measured and the feces were collected to detect gut microbiota by using 16S rRNA high-throughput sequencing method.Results:The higher proportion and abundance of Firmicutesbacteria and lower proportion and abundance of Bacteroidetesbacteria were found in AT group.The number and abundance of Akkermansia muciniphila in feces of RT group were significantly higher than those of AT and control groups.Lower level of blood glucose was observed in RT group relating to control group.Conclusion:Resistant exercise to improve gut microbiota is expected to be a new method for the prevention and treatment of type 2 diabetes.
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